The economic impact of accurate phenotype prediction extends beyond individual patient care. Healthcare systems worldwide face increasing pressure from antimicrobial resistance and emerging pathogens. By rapidly identifying bacterial characteristics that influence treatment efficacy—such as biofilm formation capability or inherent antibiotic resistance patterns—predictive models can help optimize antibiotic stewardship programs and reduce the development of resistant strains. This proactive approach to bacterial characterization represents a crucial tool in our ongoing battle against antimicrobial resistance.